London Esketamine Clinic

Private Esketamine treatment in London for treatment-resistant depression. Consultant-led assessments, MHRA-approved Spravato®, delivered safely in our Harley Street clinic. Book a consultation today.

A Pioneer & the first Private Clinic to offer Esketamine Treatment in the UK

London Esketamine Clinic was the first private medical clinic in the UK to offer Esketamine nasal spray (Spravato®), beginning in September 2020.

Following MHRA approval in 2020, Esketamine became a licensed treatment option for adults with moderate to severe treatment-resistant depression — typically defined as depression that has not responded to at least two different antidepressants.

As part of Nurify Medical, our clinic combines innovation with safety, offering this advanced treatment under strict clinical supervision in our Harley Street setting.

Esketamine at a Glance

Who Is Esketamine For?

Esketamine may be suitable for adults diagnosed with treatment-resistant depression.

Every patient undergoes a comprehensive consultant-led psychiatric assessment to confirm diagnosis and determine suitability. We do not offer “quick fixes.” We offer careful, evidence-based treatment pathways tailored to the individual.

Our consultant psychiatrists will guide you through:

Diagnostic confirmation
Review of previous treatments
Risk assessment
Discussion of alternative options
Clear explanation of benefits and side effects

Only once suitability is confirmed will treatment begin.

How Esketamine Is Delivered?

Esketamine is administered intranasally using a nasal spray device.

However, unlike standard medications, it is never taken at home.

Each session is delivered exclusively within our clinic under the supervision of trained clinicians. During treatment:

Blood pressure and heart rate are monitored
• Patients remain in clinic for observation
• Clinical staff are present throughout

This structured protocol ensures safety, comfort, and optimal monitoring.

What to Expect During Treatment?

Treatment typically follows an induction phase over two months:

Month 1: Two sessions per week
Month 2: One session per week

Following this phase, some patients may move to a maintenance schedule, with sessions gradually reduced depending on clinical response.

Regular psychiatric review is essential to ensure sustained improvement and long-term remission.

Patient Journey

Initial Consultation

Complete the form, email or call us to speak with a specialist.

1

Clinical Assessment

We'll review your history and ensure TMS is right for you.

2

Personalised Plan

Treatment schedule tailored to your condition and lifestyle.

3

Supervised Treatment Sessions

Attend sessions at our Harley Street clinic under clinical supervision.

4

Ongoing Review & Monitoring

We monitor your response and adjust treatment where needed.

5

Why Patients Choose London Esketamine Clinic

First Private Provider of Esketamine in the UK
CQC Registered Private Clinic
Registered Private Clinic
Consultant Psychiatrist–Led Care
Central location on Harley Street
Transparent Pricing

Take the first steps today

Book your initial consultation with our expert clinical team.

Quick response — Confidential support — Begin your recovery journey.